Posted in colon cancer

A new Chinese study has found that cooking with onions, leeks, garlic, shallots, chives and spring onions is not only tasty, but may help protect against colorectal cancer. Adults who ate the highest amounts of allium-family veges had a 79 percent lower risk of bowel (colorectal) cancer  Natural sulphur-containing compounds and antioxidants in these veges are likely to be responsible for their beneficial effects. According to a recent study, published in the Asia Pacific Journal of Cl...

A new review article discussed how early onset colorectal cancer – defined as being diagnosed at age 50 and younger – continues to steadily rise and that public health measures need to address the increased risk factors. The article was written by Frank Sinicrope, MD, an oncologist and gastroenterologist at Mayo Clinic Cancer Centre  and was published in The New England Journal of Medicine. While the research emphasised an increase in early onset colorectal cancer diagnosis...

Colon cancer is one of the most common types of cancer. Particularly in advanced stages of disease, the treatment still largely relies on traditional chemotherapy. The new generation of cancer treatments, so-called immunotherapies, has only been effective in a small subgroup of colon cancers. TU Dresden scientists led by Prof. Sebastian Zeissig have now identified proteins that are promising targets for new immunotherapies against colon cancer. Their results also underline the central role of...

Periodontal disease (PD) may increase the risk of sporadic colorectal cancer (CRC), findings from the population-based case-control COLDENT study suggest. The rate of new CRC diagnoses among individuals in the study who had a history of PD was nearly 50% higher than in those with no such history, after adjusting for a host of medical and demographic factors, say the investigators. This isn't the first time PD has been linked with extra-oral health outcomes, including gastrointestinal ca...

Colorectal cancer (CRC) is the neoplasia that is most frequently associated with vitamin D deficiency in epidemiological and observational studies in terms of incidence and mortality. Many mechanistic studies show that the active vitamin D metabolite (1α,25-dihydroxyvitamin D3 or calcitriol) inhibits proliferation and promotes epithelial differentiation of human colon carcinoma cell lines that express vitamin D receptor (VDR) via regulating a high number of genes. A key action underlin...