Evidence Based Research | Patient Resources

How long is long enough or too long when it comes to adjuvant aromatase inhibitor (AI) therapy for postmenopausal women with early-stage hormone receptorpositive (HR+) breast cancer? That's a question that has been vexing oncologists for more than a decade, but final results from a large study now suggest that after an initial 5 years of adjuvant endocrine therapy with tamoxifen and/or an AI, an additional 5 years of AI therapy offer no clinical benefits compared with an additional 2 yea...

The aim of the study was to investigate the antitumor effects of quercetin and luteolin combined with 5-Fluorouracil (5-FU) in HT-29 human colorectal cancer cells. Cell viability induced by quercetin, luteolin and combination of these compounds with 5-FU were determined by MTT assay, also Cell death detection Elisa assay and fluorescence microscopy were performed to investigate apoptotic effects. The results indicated that quercetin, luteolin and combinations of these compounds with 5-F...

Vitamin C is a nutrient found in food and dietary supplements. It is an antioxidant and also plays a key role in making collagen.  High-dose vitamin C may be taken by mouth or given by an intravenous (IV) infusion (through a vein into the bloodstream). When taken by IV infusion, vitamin C can reach higher levels in the blood than when the same amount is taken by mouth. Some studies of IV high-dose vitamin C in patients with cancer have shown improved quality of life, as well as few...

Although they were thoroughly debunked in the 1970s as anti-cancer agents, products made from apricot pits continue to be aggressively marketed to unsuspecting patients. The idea that apricot seeds could fight cancer arose because apricot pits contain a substance called amygdalin. Laboratory research into laetrile, a synthetic version of amygdalin, has produced contradictory results. Do apricot seeds fight cancer? What is vitamin B17?
The idea that such products could fight cancer ar...

Amla is the most revered medicinal berry in India, being used for myriad health issues and diseases for thousands of years. It is the foundation ingredient in Chyavanaprasha, the traditional Indian jam which is a potent antioxidant mixture aiding digestion and excretion, and rejuvenation. There is a deep spiritual connection with this fruit and its medicinal compounds, as it is thought to have been the first tree to grow on Earth, springing from Brahma's tears whilst he was meditating. ...