Posted in Immunotherapy

How Cancer Cells Escape The Backlash Of The Immune System

Posted by Manuela Boyle on 14 June 2022
How Cancer Cells Escape The Backlash Of The Immune System
T cells are the immune system's SWAT team. Their job is to constantly patrol the blood, lymphatic system, tissues, and organs. If they come across cells that are contaminated with or damaged by pathogens, they eliminate them. They can also recognise and destroy cancer cells. The problem, though, is that the tumour cells find ways of escaping this line of defence. Researchers around the world are working to prevent these evasive manoeuvres and harness T cells for targeted immunotherapies a...
Posted in:NewsEvidence Based ResearchCancerImmunotherapyImmune system  

Researchers Identify New Targets For Immunotherapy In Colon Cancer

Posted by Manuela Boyle on 3 April 2022
Researchers Identify New Targets For Immunotherapy In Colon Cancer
Colon cancer is one of the most common types of cancer. Particularly in advanced stages of disease, the treatment still largely relies on traditional chemotherapy. The new generation of cancer treatments, so-called immunotherapies, has only been effective in a small subgroup of colon cancers. TU Dresden scientists led by Prof. Sebastian Zeissig have now identified proteins that are promising targets for new immunotherapies against colon cancer. Their results also underline the central role of...
Posted in:NewsResourcesEvidence Based ResearchCancercolon cancerImmunotherapy  

Faecal Microbiota Transplant Promising For Those Resistant To Melanoma Cancer Immunotherapy

Posted by Manuela Boyle on 19 February 2022
Faecal Microbiota Transplant Promising For Those Resistant To Melanoma Cancer Immunotherapy
Cancer patients who have run out of options for immunotherapy may have a new possibility. It’s the gut microbiome. By changing the gut microbiome in advanced melanoma patients, who had previously failed to respond to treatment, the body responded to anti-PD-1 immunotherapy. Though the research is in phase II trials, it’s very positive news for those who have little hope. Researchers at UPMC Hillman Cancer Center and the National Cancer Institute (NCI) demonstrated that changing t...
Posted in:NewsEvidence Based ResearchCancerImmunotherapyMelanoma  

Immunotherapy Is Best Given Before Liver Cancer Surgery

Posted by Manuela Boyle on 21 January 2022
Immunotherapy Is Best Given Before Liver Cancer Surgery
Recent research has shown that immunotherapy given before surgery caused liver cancer tumours to die off in one-third of the patients enrolled in a first-of-its-kind clinical trial. Mount Sinai researchers reported their findings in The Lancet Gastroenterology & Hepatology - January 2022 The phase 2 trial results suggested that the neo-adjuvant immunotherapy -- therapy given before surgery -- may kill not only the tumour, but also microscopic cancer cells that surgery would miss and tha...
Posted in:NewsEvidence Based ResearchCancerImmunotherapyLiver Cancer  

KRAS Pathway Opens Door for Patients With Difficult-to-Treat Ovarian Cancer

Posted by Manuela Boyle on 9 July 2021
KRAS Pathway Opens Door for Patients With Difficult-to-Treat Ovarian Cancer
Dual blockade of the RAF/MEK and FAK pathways presents an opportunity for investigators to enhance and expand the number of patients with recurrent low-grade serous ovarian cancer (LGSOC) who can benefit from targeted therapies. LGSOC, which accounts for between 1.02% and 3.64% of all ovarian carcinomas and 4.66% of serous ovarian carcinomas1, is molecularly unique from high-grade serous ovarian cancer (HGSOC) with approximately 70% of patients harboring a RAS pathway- associated mutation:...
Posted in:NewsCancerOvarian cancerImmunotherapy  

Associations

  • The Institute for Functional Medicine
  • Society for Integrative Oncology
  • American Society of Clinical Oncology
  • Australian Traditional-Medicine Society
  • Naturopaths and Herbalists Association of Australia