Cancer cells are well documented to rewire their metabolism and energy production networks to support and enable rapid proliferation, continuous growth, survival in harsh conditions, invasion, metastasis, and resistance to cancer treatments. Some of the most striking changes of tumor cellular bioenergetics include elevation of glycolysis, increase in glutaminolytic flux, upregulation of amino acid and lipid metabolism, enhancement of mitochondrial biogenesis, induction of pentose phosphat...

A study, published in the peer-reviewed journal "Addictive Behaviours", has found telling people that alcohol causes cancer makes them want to drink less. Author Simone Pettigrew, from The George Institute for Global Health, had 8000 adults complete three surveys. She said alcohol was associated with increased risk of injury and premature death and even moderate drinkers were at risk of some cancers. "We found pairing information about alcohol and cancer with ... counting t...

Metabolic reprogramming is a major hallmark of cancer, which is characterized by upregulated glycolysis, glutaminolysis, lipid metabolism, pentose phosphate pathway, mitochondrial biogenesis, among others. These metabolic programs provide cancer cells with not only energy but also vital metabolites to support large-scale biosynthesis, continuous proliferation and other major processes of tumorigenesis. Potent oncogenes as c-Myc, HIF1, Ras and PI3K/Akt are important promoters of cancer meta...

The Australian Medical Association (AMA) has demanded a tax on high-sugar drinks and shown support for an increase in alcohol prices. AMA president Dr Omar Khorshid said the group would call for a 20 per cent tax on high-sugar beverages in a bid to cut "skyrocketing" rates of diabetes, obesity and cardiovascular disease. He said the tax received widespread support in the community, and also flagged his support for increased alcohol prices, either via higher volumetric taxes or a...

The Prostate Cancer Foundation of Australia (PCFA) has co-funded a new clinical trial aimed at preventing the deaths of 3000 Australian men a year. The trial will investigate the effectiveness of new radiotherapy treatment with existing forms of immunotherapy in treating aggressive forms of prostate cancer.

The Courier Mail; 11/06/2021; Page 10