Studies have shown that the gut microbiota could influence the response of melanoma to anti–PD-1 immunotherapy. It is known that only 30%-40% of melanoma patients respond to anti–PD-1 immunotherapy, so the researchers focused on the gut microbiota of adult male patients. For the study, which was funded by the National Institutes of Health and published in Science, Professor Zarour and a team of colleagues, including Dr Diwakar Davar, MD, a Medical Oncologist/haematologist at...

Amid a modern backdrop of common lifestyle-related illnesses, dietary quality has emerged as both a risk and an opportunity for health. Research increasingly focuses upon the importance of nutrient density, intakes of phytonutrient often lacking in modern diets, and in the functionality of foods’ macronutrient profiles. To definitively address the gut microbiome imbalances that result in disease for many individuals, there is heightened interest in ancient species of plant foods that ...

Due to their high concentration of catechins and procyanidins, bioactive compounds with distinct properties, cocoa and chocolate products may have beneficial health effects against oxidative stress and chronic inflammation. In moderation, cocoa products may offer powerful antioxidant effects in combination with a pleasurable eating experience. The benign profile of its fatty acids in combination with the low content of sugar of dark chocolate should lessen concerns about the adverse effects...

A cancer support group provides a place to discuss fears and challenges with others you know who are going through the same thing. Complex social interactions have been a cornerstone of human evolution, altering how we respond to stress and immune challenges, the environment, and one other. Our history as hunter/gatherers has much to do with patterns in behaviour and metabolism that are not always adaptive in modern contexts, and adverse social circumstances have been linked with heart disea...

Follicular lymphomas (FL) are a type of non-Hodgkin’s lymphomas that most times respond very well to chemotherapy treatments (first-line therapy). Follicular lymphoma are associated with the over expression of Bcl-2 and chromosomal translocation (14;18), leading to deregulated apoptosis. As Bcl-2 is an important negative regulator of the mitochondrial pathway, novel therapeutic approaches circumventing the mitochondrial block may prove useful to treat these patients. A few unconve...