Evidence Based Research | Patient Resources

Chimeric antigen receptor (CAR) T-cell therapy has the potential to replace chemoimmunotherapy for second-line treatment of patients with large B-cell lymphoma (LBCL) that have relapsed or are refractory to first-line therapy, results of the phase 3 ZUMA-7 and TRANSFORM trials suggest. In the ZUMA-7 trial, at a median follow-up of 24.9 months, patients randomly assigned to receive CAR T-cell therapy with axicabtagene ciloleucel, or axi-cell (Yescarta) had a median event-free survival (EFS) o...

Numerous studies have shown that coffee drinking is associated with a lower risk of dying from all causes of death. However, associations with cancer overall or with specific types of cancer are unclear. In 2016, an expert working group convened for the International Agency for Research on Cancer Monographs Programme reviewed the world’s body of human and laboratory research on coffee drinking and cancer risk, and they found evidence of carcinogenicity of coffee drinking to be “...

The papaya or pawpaw (Carica papaya) is a tropical fruit, which has been consistently associated with numerous medicinal properties. One of the most important of these claims is the ability of papaya leaf extract to revert low platelet counts to normal in dengue fever. Several researchers have tested preparations of papaya leaf, in particular, in regard to the platelet count. One systematic review confirmed the increase in platelet count to be more significant in the group that received the...

A randomised controlled trial investigated the effect of Qigong in patients diagnosed with lung cancer. Qigong is an ancient system of exercises rooted in ancient Chinese philosophy. They are designed to cultivate and influence “Qi” in order to improve the health and harmony of the mind and body. This is done by coordinating the breath with gentle movements and visualisation while standing and moving through set sequences. There are literally thousands of different examples and s...

Omega-3 fatty acids have been extensively researched for their immune, cognitive, developmental, visual, skin, and cardiovascular influences. It was previously thought that omega-3 fatty acids like eicosapentaenoic acid, docosahexaenoic acid, and docosapentaenoic acid (EPA, DHA, and DPA) modulate inflammatory processes primarily by interfering with the metabolism of arachidonic acid. More recent research has discovered that metabolites of omega-3 fats influence the course of an inflammatory...