Posted in Inflammation

Researchers from Columbia University Vagelos College of Physicians and Surgeons set out to investigate the impact of the typical Western-style diet of the microbiome on mice. In the four-week study, scientists found that the mice showed signs of metabolic syndrome, including weight gain, glucose intolerance, and insulin resistance. Moreover, the animals’s microbiomes were altered — segmented filamentous bacteria (found in rodents, fish, and chickens) decreased and other bacteria ...

In 1984, Bernard Bihari, MD, a Harvard University physician and researcher, observed that while naltrexone successfully blocked heroin’s ability to bind the opioid receptors, the complete blockage led to such severe side effects that the former addicts would not comply with continued use. With his knowledge of naltrexone’s effect on the immune system, he turned his research attention in that direction. Realising that naltrexone’s effects included increasing endorphins and t...

Since the discovery of Celiac disease (CD), the mainstream view of gluten intolerance has remained relatively black or white: Either you have celiac disease, or you don't. The media has downplayed the significance of non-celiac gluten sensitivity (NCGS), even going as far as to suggest that it doesn't exist. However, it's becoming more and more clear that celiac disease is only one manifestation of gluten intolerance, and that "non-celiac gluten sensitivity" (i.e. pe...

Inflammasone has a relationship with obesity-related colon cancer. According to recent evidence-based research, dysregulation of inflammasomes could be a significant factor in the development of obesity-associated colon cancer. When this part of the innate immune system, which provides the first line of defence against pathogens, is exposed to prolonged inflammation from visceral adipose tissue (VAT), it increases the risk of obesity-related colon cancer.
Dysregulation of inflammasomes wit...