Posted in Functional and Integrative Testing

Zonulin is a protein that modulates the permeability of tight junctions between cells of the wall of the digestive tract. It was discovered in 2000 by Alessio Fasano and his team at the University of Maryland School of Medicine. As the mammalian analog of zonula occludens toxin, secreted by cholera pathogen Vibrio cholerae, zonulin has been implicated in the pathogenesis of celiac disease and diabetes mellitus type 1. Type 2 diabetic patients have shown increased zonulin. “The amazing...

The GPL-TOX profile test is one of the most accurate ways to check for level of exposure to toxic chemicals. Once a positive test is identified, there are things you can do to help your body eliminate the toxins and to prevent future exposures. Phthalates Perhaps the most widespread group of toxic chemicals found in our environment. Phthalates are commonly found in after shave lotions, aspirin, cosmetics, detergents, foods microwaved with plastic covers, oral pharmaceutical drugs, intr...

There’s a theory—and a reasonable one—that as inflammation increases, the amount of oxidative free radicals also increases, and they eventually “spill-over” and disrupt neurotransmitter formation.  Initially, neurotransmitter production increases in response to stressors, but over time inflammation-related free radicals will interrupt Cortisol curve neurotransmitter production, ultimately leading to depletion. Some researchers have suggested that the brain ...