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ASC and Epigenetics 2019

Posted by Vitawell on 22 September 2020
Oral vitamin C supplementation to patients with myeloid cancer on azacitidine treatment: Normalization of plasma vitamin C induces epigenetic changes is a research paper from Clinical Epigenetics. "Patients with haematological malignancies are often vitamin C deficient, and vitamin C is essential for the TET-induced conversion of 5-methylcytosine (5mC) to 5-hydroxymethylcytosine (5hmC), the first step in active DNA demethylation. Here, we investigate whether oral vitamin C supplement...
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Cancer cachexia: understanding the molecular basis

Posted by Vitawell on 22 September 2020
Cancer cachexia: understanding the molecular basis is an article from Nature Reviews. "Cancer cachexia is a devastating, multifactorial and often irreversible syndrome that affects around 5080% of cancer patients, depending on the tumour type, and that leads to substantial weight loss, primarily from loss of skeletal muscle and body fat. Since cachexia may account for up to 20% of cancer deaths, understanding the underlying molecular mechanisms is essential. The occurrence of cachexi...
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Drug repurposing in oncology: Compounds, pathways, phenotypes and computational approaches for colorectal cancer

Posted by Vitawell on 22 September 2020
Drug repurposing in oncology: Compounds, pathways, phenotypes and computational approaches for colorectal cancer is an article from Biochim Biophys Acta Rev Cancer. "The idea of using known and approved drugs for new indications has recently gained considerable momentum in many fields of medicine, especially in complex disorders. This approach presents an important advantage, as compared to the "de novo" drug discovery process, by considerably reducing the cost and time to ...
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Inflammation meets cancer, with NF-κB as the matchmaker

Posted by Vitawell on 22 September 2020
Inflammation meets cancer, with NF-kB as the matchmaker is an article from Nature Immunology. "Inflammation is a fundamental protective response that sometimes goes awry and becomes a major cofactor in the pathogenesis of many chronic human diseases, including cancer. Here we review the evolutionary relationship and opposing functions of the transcription factor NF-kB in inflammation and cancer. Although it seems to fulfill a distinctly tumor-promoting role in many types of cancer, N...
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Interview: Manuela Boyle

Posted by Manuela Boyle on 22 September 2020
Interview: Manuela Boyle is an interview with our very own Manuela Boyle from The Art of Healing. "Manuela Boyle PhD MHSc MPhil NMD FIO is a world-renowned integrative medicine oncologist who has a fellowship from the University of Arizona, United States, and master degrees from the University of Queensland and the University of New England, Australia. Manuela has over 20 years of clinical experience as an international consultant (particularly with cancer patients) and is the creato...
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Associations

  • The Institute for Functional Medicine
  • Society for Integrative Oncology
  • American Society of Clinical Oncology
  • Australian Traditional-Medicine Society
  • Naturopaths and Herbalists Association of Australia