Posted in Joint Health

Cortisol is a glucocorticoid hormone synthesised from cholesterol in the cortex of the adrenal gland. Cortisol has a variety of functions but is primarily known for its role in the body’s stress response.  Cortisol also participates in the inflammatory response and regulation of metabolism. Glucocorticoids, such as cortisol, bind to both glucocorticoid receptors (GRs) and mineralocorticoid receptors (MRs). GRs exist in almost all tissues in the human body. MRs have a more restrict...