Posted in Cancer Metabolism

Cancer cells are well documented to rewire their metabolism and energy production networks to support and enable rapid proliferation, continuous growth, survival in harsh conditions, invasion, metastasis, and resistance to cancer treatments. Some of the most striking changes of tumor cellular bioenergetics include elevation of glycolysis, increase in glutaminolytic flux, upregulation of amino acid and lipid metabolism, enhancement of mitochondrial biogenesis, induction of pentose phosphat...