Posted by Manuela Boyle
on 24 April 2021
Diindolymethane (DIIM) is a metabolite generated when the stomach breaks down Indole-3-Carbinol (I3C) found in cruciferous vegetables like broccoli, kale, bok choy, cabbage, cauliflower, collards, kale, Brussels sprouts, and kohlrabi. Once consumed, the bioactive constituents are rapidly metabolized into several intermediate and end products. As an antioxidant, this phytonutrient has shown to promote healthy oestrogen metabolism in both men and women. An appropriate oestrogen metabolism optimises the ratios of oestrogen but also progesterone and testosterone in the body. In order to get the recommended daily amount of DIIM, one would have to consume at least 1 kilogram of these vegetables daily. This is the reason why we recommend supplementation.
Thomson, C. A., Ho, E., & Strom, M. B. (2016). Chemopreventive properties of 3,3'-diindolylmethane in breast cancer: evidence from experimental and human studies. Nutrition reviews, 74(7), 432443. https://doi.org/10.1093/nutrit/nuw010