How old you really are?

When a person is asked how old they are, the number of years since their birth is a typical response. However, if age is measured in terms of biology, individuals of the same chronological age may be older or younger at the epigenomic level.

While epigenetic aging is an integral part of the overall aging process, external factors such as diet and eating patterns may impact the speed of biological aging and ultimately an individual's health span.

New research evaluates the mechanisms by which therapeutic fasting alters the expression of genes and microbiota relevant to aging and longevity in humans. This new data may provide key insights into addressing differing susceptibilities or risk levels for age-related diseases.

References

Chen C, Zhou M, Ge Y, Wang X. SIRT1 and aging related signaling pathways. Mech Ageing Dev. 2020;187:111215. doi:10.1016/j.mad.2020.111215